C04978: Novel, Multi-Surface, Laser based Protein Patterning TechnologyNovelty:
The patterning technology uses a fundamentally different approach to patterning by using an ablation laser to remove molecules from substrate surfaces and thereby patterns to produce unique custom research tools.
Value Proposition:
The current technology is a fundamentally different approach to patterning wherein an ablation laser is used to remove molecules to design patterns rather than add molecules as done conventionally. Other advantages include:
• Uses a “writing” approach to enhance flexibility as opposed to the conventional lithographic approach.
• Allows for patterning of many different molecule types and more importantly can pattern gradients as well.
• Works on a wide range of surface shapes and compositions.
• Works effectively in a wide range of environmental conditions (dry, hydrated, aqueous etc.).
• Wide applications in tissue engineering, biochip design, sensor design and discovery based research tools.
Technical Details:
Johns Hopkins researchers have discovered ablation based laser machining as a novel approach to protein patterning on surfaces. The technology is highly versatile and works essentially for any molecule that can be immobilized on a wide variety of surface shapes and chemistries.
Looking for Partners:
To develop & commercialize the technology as unique approach to protein patterning as well as explore other applications in the field of biochip design.
Stage of Development:
Prototype
Data Availability:
Under CDA / NDA
Publications/Associated Cases:
Lab Chip, 2011, 11, 3336-3346 , C11519, C10670, C10653, C10621
