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N171-82Q Huntington's Disease (HD) Mouse Model
Case ID:
C05027
Report of Invention:
7/24/2006
Web Published:
10/7/2014
C05027: N171-82Q Huntington's Disease (HD) Mouse Model
Technical Details:
This transgenic line expresses an N-terminally truncated human huntingtin cDNA that encodes 82 glutamines and encompasses the first 171 amino acids. The altered huntingtin cDNA is under the control of a mouse prion protein promoter. Expression is observed in neurons of the central nervous system.
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This mouse model provides an important research tool for studying the pathogenesis of Huntington?s disease.
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Direct Link:
https://jhu.technologypublisher.com/technology/16476
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Category(s):
Clinical and Disease Specializations, Clinical and Disease Specializations > Neurology > Huntington's Disease, Clinical and Disease Specializations > Neurology > Neurodegeneration, Clinical and Disease Specializations > Rare Diseases, Technology Classifications > Research Tools > Animal Models, Technology Classifications > Research Tools > Cell Lines, Clinical and Disease Specializations > Neurology, Technology Classifications > Research Tools,
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For Information, Contact:
Nakisha Holder
nickki@jhu.edu
410-614-0300
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