C05074: Coronary Artery Disease ScanNovelty:
A new imaging study that gives detailed diagnostic information for Coronary Artery Disease.
Value Proposition:
The diagnosis of Coronary Artery Disease (CAD) is commonly performed through imaging studies. Myocardial perfusion imaging (MPI) uses single photon emission tomography to assess the physiological significance of a stenosis, but does not require a high spatial resolution. On the other hand, advances in multi-detector, or multislice, computed tomography (MDCT) acquisition technologies have yielded robust systems which achieve both high speed and high resolution. However, MDCT coronary angiography currently lacks the ability to determine the physiological significance of a coronary stenosis. This technology provides a means to determine both the location and severity of stenosis in a patient with just a single scan. Other advantages include:
• Can assess cases that are “Un-evaluable” by MDCT angiography alone
• Reduced dosage to patient
• Improved diagnostic efficiency
Technical Details:
Johns Hopkins researchers have developed a method to incorporate MPI into MDCT coronary angiography. Combining these methods has allows for examination of coronary arteries for stenoses and simultaneous measurement of myocardial blood flow. This provides for a rapid detailed analysis so that patients can be properly assessed, without the need for multiple studies.
Looking for Partners:
To develop and commercialize the technology as a new diagnostic method in the coronary imaging market
Stage of Development:
Prototype
Data Availability:
Imaging data on six dogs with moderate to severe descending artery stenosis
Publications/Associated Cases:
J Am Coll Cardiol. 2006;48(1):153-160
