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293 Cell Line for Flag-tagged HIMF (flag-HIMF-293)
Case ID:
C05157
Report of Invention:
1/9/2007
Web Published:
10/7/2014
C05157: 293 Cell Line for Flag-tagged HIMF (flag-HIMF-293)
Technical Details:
Hypoxia-induced mitogenic factor (HIMF) is highly up regulated in the lungs as a result of hypoxia-induced pulmonary hypertension, and has proangiogenic and proinflammatory effects in the lung. As a research tool for studying the function and activity of HIMF, JHU researchers have developed a transgenic HEK 293 cell line expresses a Flag-tagged HIMF. Expression of the Flag-tagged HIMF protein can be induced by tetracycline and most of the protein is secreted into the culture medium where it can be readily purified by column chromatography.
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This cell line model provides an important research tool for studying the function and activity of HIMF.
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Direct Link:
https://jhu.technologypublisher.com/technology/16511
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Category(s):
Technology Classifications > Research Tools > Cell Lines, Technology Classifications > Research Tools > Human Cell Lines, Technology Classifications > Research Tools,
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For Information, Contact:
Heather Curran
hpretty2@jhu.edu
410-614-0300
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