C10036: Estrogen Receptor in Knock out (ERIK) Cells
Technical Details:
Receptor positive non-tumorigenic human breast epithelial cell line derived from the commercially available MCF-10A human breast epithelial cell line with the p21 gene somatically deleted.
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The cell lines described in this invention can be used in screens for novel molecules target ER+ positive breast cancer or to confirm the specificity of drugs discovered through other approaches. Such drugs can potentially be used as chemotherapeutic or chemopreventive agents
