A Neuroprotective Agent with Applicability to Glaucoma, Optic Nerve Diseases, and other Neurodegenerations

Case ID:
C10454
Disclosure Date:
7/17/2008

C10454: Known Drug found to have applicability in the area of glaucoma, optic nerve diseases, and other neurodegenerations

Value Proposition:

Key Features • Provides treatment for glaucoma, other optic nerve diseases, and potentially any disease with neuronal dysfunction or loss. • Exploits an FDA approved drug, which may reduce clinical hurdles and time to market.

Technical Details:

According to the World Health Organization, glaucoma is the second leading cause of blindness in the world. One approach to treat glaucoma, and optic nerve diseases as well as other neurodegenerations, is to develop “neuroprotective” agents that promote the survival of neurons. JHU scientists have made a discovery that a known drug has a novel function as a neuroprotective agent that promotes the survival and neurite outgrowth of retinal ganglion cells (RGCs), the cells in the retina that die in glaucoma and whose loss leads to vision loss.

Looking for Partners:

Small molecule for treatment of glaucoma, optic nerve diseases, and other neurodegenerations.



Patent Information:
Title App Type Country Serial No. Patent No. File Date Issued Date Expire Date Patent Status
Compositions and Methods for Treatment of Neurodegenerative Disease PCT: Patent Cooperation Treaty United States 13/058,171 8,993,615 4/4/2011 3/31/2015 4/27/2031 Granted
Compositions and Methods for Treatment of Neurodegenerative Disease DIV: Divisional United States 14/626,524 9,655,882 2/19/2015 5/23/2017 11/14/2029 Granted
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For Information, Contact:
Vera Sampels
vsampel2@jhu.edu
410-614-0300
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