Cholesterol Treatment of Autism Spectrum Disorder

Case ID:
C10705
Disclosure Date:
4/3/2009

C10705: Autism Spectrum Disorder: A Treatment Approach

Value Proposition:

While there is no known single cause for autism, Inventors have determined that a population of patients with ASD that is not associated with Smith-Lemli-Opitz Syndrome has plasma sterol levels that are outside the typical range. Preliminary studies by the Inventors suggest that optimizing plasma sterol levels has a beneficial effect on social interactions, verbal and non-verbal communication. This concept can be developed into a treatment method for a subpopulation of patients with ASD by optimizing plasma sterol levels. A clinical trial is in progress.

ADVANTAGES
- Treatment method supplements a measurable deficit in serum sterol levels in a population of patients with Autism Spectrum Disorders that is not associated with Smith-Lemli-Opitz Syndrome and can increase social, verbal and non-verbal behaviors for improved quality of life in patients and their families.
- Therapeutic dietary supplement could potentially be developed with a variety of textures and flavors in order to increase compliance in a patient population with heightened sensitivities to food and drink.

Technical Details:

Autism is a complex developmental disability caused by neurological issues. It affects 1 in every 150 American children, and almost 1 in 94 boys. Autism is a spectrum disorder that affects each individual differently and at varying degrees. Both children and adults with Autism Spectrum Disorder (ASD) show difficulties in social interactions, verbal and non-verbal communication, and play activities. There is an unmet medical need for ways to improve development in social interaction and communication skills.

Looking for Partners:

This technology could be commercialized as a method to treat the symptoms of Autism Spectrum Disorder. The technology could be developed into a therapeutic supplement for patients with Autism Spectrum Disorder.



Patent Information:
Title App Type Country Serial No. Patent No. File Date Issued Date Expire Date Patent Status
METHODS FOR TREATMENT OF AUTISM SPECTRUM DISORDER ORD: Ordinary Utility United States 13/945,384 8,987,246 7/18/2013 3/24/2015 7/18/2033 Granted
Inventors:
Category(s):
Get custom alerts for techs in these categories/from these inventors:
For Information, Contact:
Nakisha Holder
nickki@jhu.edu
410-614-0300
Save This Technology:
2017 - 2022 © Johns Hopkins Technology Ventures. All Rights Reserved. Powered by Inteum