Johns Hopkins researchers have developed a composition comprising a biologically compatible polymer functionalized by at least two different reactive moieties to provide a biological adhesive.
Technical Details:
A useful biomaterial mimics a naturally occurring material, tissue, organ and the like. However, ease of administration, biocompatibility, biodegradability and other requirements for in vivo use can constrain the full use of a material. Polymer networks may be formed, for example, by crosslinking water soluble monomers or polymers to form a water insoluble polymer network. Mechanical and structural properties may be manipulated by modification of the crosslinking density which controls, for example, network pore size, water content and mechanical properties.
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Numerous applications including coatings for medical devices, implants and drug delivery vehicles