C10996: Method for Determining Ventricular Arrhythmia Risk Based on Analysis of ECG RecordingNovelty:
The novel analytics could potentially be used to distinguish those patients with cardiac conditions that could be helped by an ICD from those that are not likely to benefit from an ICD.
Value Proposition:
Sudden cardiac death (SCD) from abnormal heart rhythms strikes about 350,000 victims in the U.S. every year. Implantable cardioverter defibrillators (ICDs) are the treatment of choice for patients at risk for SCD. However, only a subpopulation of at-risk patients will benefit from having ICD devices. This invention can easily distinguish patients whose abnormal heart rhythms can be managed with an ICD implant from patients who are not ideal candidates for an ICD. Other advantages include:
• Ability to identify patients most at risk for Sudden Cardiac Death (SCD) so that they can be effectively treated and monitored to reduce unexpected death.
• Novel analytic method employs routinely produced ECG data for ease of use.
• Novel ECG data analysis reduces unnecessary implantation of cardiac devices in patients that would not benefit from them to decrease expense and patient stress.
• Method to assess patients who would most benefit from an ICD implantation is relatively inexpensive if used with existing ECG equipment and devices.
• May be applied for both long-term risk stratification and short-term prediction of dangerous abnormal heart rhythms.
Technical Details:
Many heart functions are analyzed with Electrocardiography measurements. JHU scientists have developed novel analytical calculations for electrocardiogram readings to gauge the risk of life-threatening abnormal heart rhythms and stratify at-risk candidates for ICD implantation.
Looking for Partners:
This technology could potentially be commercialized as a method to determine risk of sudden cardiac death.
Publications/Associated Cases:
1. Heart Rhythm. 2010 Nov;7(11):1606-13
2. J Electrocardiol. 2010 Nov-Dec;43(6):548-52
