Image Processing Method for Fluoroperfusion

Case ID:
C11290
Disclosure Date:
11/9/2010

C11290: Image Processing Method for Fluoroperfusion

Novelty:

The current invention is a novel method to enhance Fluoroperfusion imaging contrast.

Value Proposition:

Evaluation of myocardial perfusion using Fluoroscopy is important for guiding invasive therapies for obstructive coronary artery disease. Conventional simple baseline subtraction that determines the level of signal intensity does not work well in quantitative analysis. One possible factor is accumulated huge amount of contrast agent that is injected many times from the beginning of coronary intervention. This new image processing method solves the above problems has and includes the following advantages:

• The method uses initial baseline data that is acquired very beginning of the procedure for normalization
• Accurate assessment of myocardial perfusion imaging during invasive coronary angiography
• Allows robust quantitative analysis

Technical Details:

Johns Hopkins researchers have developed a method for Fluoroperfusion imaging. This method allows quantitative analysis of myocardial perfusion and flow reserve during invasive coronary angiography. Previously, this required direct measurement using an intracoronary wire to measure intracoronary pressure or blood flow.

Looking for Partners:

To develop and commercialize the technology as a method for image processing for evaluation of myocardium perfusion.

Stage of Development:

Proof of Concept

Data Availability:

Under CDA/NDA

Publications/Associated Cases:

C10346 X-ray CT Apparatus and Myocardial Blood Flow Amount Image Display System

Patent Information:
Title App Type Country Serial No. Patent No. File Date Issued Date Expire Date Patent Status
Image Processing Method for Fluoroperfusion PCT: Patent Cooperation Treaty European Patent Office 11839867.6 2638856 11/8/2011 12/25/2019 11/8/2031 Granted
Image Processing Method for Fluoroperfusion ORD: Ordinary Utility Japan 2011-244817 5911268 11/8/2011 4/8/2016 11/8/2031 Granted
Image Processing Method for Fluoroperfusion PCT: Patent Cooperation Treaty Germany 60 2011 064 276.6 2638856 11/8/2011 12/25/2019 11/8/2031 Granted
Image Processing Method for Fluoroperfusion PCT: Patent Cooperation Treaty Netherlands 11839867.6 2638856 11/8/2011 12/25/2019 11/8/2031 Granted
Image Processing Method for Fluoroperfusion PCT: Patent Cooperation Treaty China 201180004810.9 ZL 201180004810.9 11/8/2011 1/6/2016 11/8/2031 Granted
Image Processing Method for Fluoroperfusion PCT: Patent Cooperation Treaty United States 13/886,910 8,965,085 5/3/2013 2/24/2015 11/10/2030 Granted
Inventors:
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For Information, Contact:
Louis Mari
lmari3@jhu.edu
410-614-0300
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