C11321: System for Improved Pathology Specimen Evaluation
Novelty:
This technology is a system to dramatically improve the ease and efficiency of evaluation of pathology slide specimens.
Value Proposition:
The current navigation paradigm in digital microscopy relies on a computer mouse or other input device to "drag" the displayed image from one location to another. The drawbacks associated with current methods indicate a need for quicker, more robust automated methods to review pathologic samples for the diagnosis of disease. The system will re-orient tissue from any angle into a single linear direction and records the position of the tissue on the glass slide and marks the areas of the slide that have been viewed. Key advantages of this technology are:
• Algorithm to design a minimally overlapping tiling set across the tissue
• Efficient user interface
• Presentation of a series of static images, rather than a single moving image method to interpret the material on the digital glass slide
• A timing mechanism to mark the time spent on each image to identify tiles that were viewed for the longest time. This is to be used to automatically identify areas of interest to allow "highlights of the slide" to be presented for re-review of the slide material.
Technical Details:
Johns Hopkins University researchers have developed systems and methods for automated digital light microscopy pathologic imaging useful for disease diagnosis. The developed software is applicable to current digital pathology systems for a quicker, more robust method to move from point A to point B. Specifically, the method and system will take a digital pathology image, reorient the image, generate a series of images that represents the minimal set of overlapping tiled images required to cover all tissue present on the slide and present the series of the images to the user with a forward/back mechanism for scrolling through the material. This improvement removes the step of continually repositioning the slide which is time consuming, can lead to eye and mental fatigue and can result in missing areas of the slide containing tissue. It also has the ability to track and time an investigators work to record the areas of the slide viewed.
Looking for Partners:
To develop and commercialize the technology for digital evaluation of pathology slide specimens in clinical and research settings for needle or endoscopic biopsy interpretation of surgical pathology biopsies (skin, breast, prostate, liver, kidney, GI trad).
Stage of Development:
Prototype
Data Availability:
Under CDA/NDA
Publications/Associated Cases:
Not available at this time.
