Value Proposition:
This technology involves GN11 cells obtained from a tumor in mice containing a transgene consisting of a human GnRH promoter fused to the SV40 Large TAntigen oncogene (Tag). GN11 cells are immortalized, gonadotropin-releasing hormone (GnRH) expressing cell lines.
Publications/Associated Cases:
Novaira HJ, et. al. Kisspeptin increases GnRH mRNA expression and secretion in GnRH secreting neuronal cell lines. Mol Cell Endocrinol. 2009 Nov 13;311(1-2):126-34. PUBMED ID: 19576263.
