Method for Registration and Enhanced Visualization in X-ray Radiographs

Case ID:
C12329

C12329: Method for Registration and Enhanced Visualization in X-Ray Radiographs

Novelty:

This invention enables 9 degrees of freedom (DoF) for 3D-2D image registration for radiographic X-ray based medical imaging devices. It enables registration in scenarios where position of X-ray is unconstrained to the detector.

Value Proposition:

Conventional methods for solving the 3D-2D registration problem during X-ray detection are limited in their ability to solve higher-order Degrees of Freedom (DoF) systems. This poses a problem when the position of X-ray source can be unconstrained with respect to the detector. The current invention is able to provide a solution where conventional methods cannot, and also provides the following advantages:

• Solves 9 DoF as compared to conventional methods which solve 6 DoF
• Enhances visualization, detection and verification of surgical product registration process
• It also facilitates visualizing anatomical changes and detecting retained foreign bodies

Technical Details:

Johns Hopkins Researchers have developed a 3D-2D image registration software that allows for additional degrees of freedom in system geometry. The method mainly involves the registration of preoperative or intraoperative 3D CT images to intraoperative 2 D x-rays. The invention solves the 3D-2D registration without any constraints on the x-ray source-detector geometry and allows registration on systems where the x-ray source is positioned independently of the x-ray detector, as typical of a mobile x-ray radiography system. This amounts to solving the full 9 DoFs of the system. The invention enhances the ability to visualize, verify, and document the surgical product by registering and fusing image and planning information defined in preoperative or intraoperative 3D images with the intraoperative 2D radiographic scene.

Looking for Partners:

To develop and commercialize the technology to be incorporated in medical equipment for mobile x-ray radiography.

Stage of Development:

Prototype

Data Availability:

Under CDA/NDA

Publications/Associated Cases:

Verification of surgical product and detection of retained foreign bodies using 3D-2D registration in intraoperative mobile radiographs.(CARS, 2013)

Patent Information:
Title App Type Country Serial No. Patent No. File Date Issued Date Expire Date Patent Status
Method for Registration and Enhanced Visualization in X-ray Radiographs ORD: Ordinary Utility United States 13/888,772 9,165,362 5/7/2013 10/20/2015 12/31/2033 Granted
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For Information, Contact:
Lisa Schwier
lschwie2@jhu.edu
410-614-0300
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