Integration of T2-preparation and motion tracking in Magnetic Resonance

C12427: Integration of T2-Preparation and Motion Tracking in MRI

Novelty:

A method for improving T2-weighted magnetic resonance imaging (MRI) in the presence of patient motion.

Value Proposition:

MRI is an indispensible medical imaging modality, primarily because of its ability to distinguish among a wide variety of human tissues and tissue pathologies. However, MRI is a relatively slow imaging technique and therefore motion artifact in images is inevitable. This technology allows for the concurrent measurement of motion during T2-weighted imaging without increasing total imaging time. Additional advantages of this imaging technology include:

Technical Details:

Johns Hopkins researchers have developed a system for integrating motion tracking and T2 preparation (T2 Prep) for the expedition of more efficient motion compensation during T2-weighted imaging or spectroscopy. T2 Prep is a standard module used to impart T2 contrast in T2-weighted MR imaging. Generally, transverse magnetizations for MRI are generated by RF excitation of the imaged subject, and the transverse magnetizations are subsequently measured. This technology collects MR image gradient readouts in between RF pulses. Identification of motion from consecutive image readouts allows for motion field mapping and post-hoc correction of subject motion during MR imaging. For example, using this technology, sufficient motion information could be extracted for tracking and correction of respiratory displacement of the heart and the affine or nonrigid motion of the abdomen, allowing for improved abdominal and cardiac MRI. In its current form, this methodology incorporates the motion measurement, tracking, and correction into a T2 Prep module.

Looking for Partners:

To develop & commercialize the technology as an add-on upgrade for motion compensation in new or existing MRI scanners.

Stage of Development:

Discovery

Data Availability:

Under CDA/NDA