C12563: Multiple Source / Single Detector System for 3D-2D Image Registration
Novelty:
The technology is a system and method for registration of 3D volumetric images to 2D images using a single X-ray detector for multiple emitters.
Value Proposition:
Surgical procedures depend on pre-operative registration for being successful. The accuracy of registration depends on how well the system can infer data from 3D image and identify the parts to be operated on a 2D image. The inventors have developed this technology to achieve accurate 3D-2D registration as well as reducing exposure of the patient to X-ray radiation. The advantages of this invention are:
- A single detector being exposed by a plurality of X-ray sources for imaging and/or 3D-2D registration
- Embodiment in which the auxiliary source(s) is operated at reduced levels of X-ray exposure that is sufficient for 3D-2D registration
- Ability to solve the 3D-2D registration with improved accuracy in 3D localization
- Improved physical and operational characteristics relative to conventional bi-plane systems
- Incorporating 2 or more X-ray sources with a single x-ray detector presents a simpler, less costly, faster, more streamlined system than conventional bi-plane
Technical Details:
Johns Hopkins researchers have developed a novel technique for better image quality and accurate image registration during pre-operative process of a surgery. They used two X-ray at small angular separation of 15-20 degrees on a C-arm, collimating on a single detector. Embodiment of the x-ray sources and single detector on a common platform makes the invention potentially more streamlined, less costly, less obtrusive, and faster to the operating environment. Using two or more projection images acquired at disparate perspectives provides accurate 3D localization in the 3D domain of the patient suitable to surgical guidance. The invention is suitable to a variety of interventional C-arm platforms such as mobile, fixed-room, robotic as common in image-guided surgery and interventional radiology as well as linear accelerator platforms common in image-guided radiation therapy.
Looking for Partners:
To develop and commercialize the technology as an improved and more accurate 3D-2D pre-operative image registration device.
Stage of Development:
Prototype
Data Availability:
Under CDA/NDA
Publications/Associated Cases:
1. PMB Article: 3D2D Registration Enables Surgical Guidance;
2. Article: New Guidance System Could Improve Minimally Invasive Surgery;
3. One abstract accepted at SPIE 2014