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CTD110.6 monoclonal antibody
Case ID:
C03770
Report of Invention:
10/6/2000
Web Published:
3/24/2015
C03770: CTD110.6 monoclonal antibody
Technical Details:
O-linked N-acetylglucosamine (O-GlcNAc) is a newly described but ubiquitous dynamic modification of key regulatory proteins in side virtually all multi-cellular eukaryotic cells. Recently, this sugar modification has been shown to be as abundant as protein phosphorylation, often competing with this key regulatory switch in the cell?s regulatory pathways. O-GlcNAc is now implicated to play an important role in diabetes, cancer and neurodegenerative diseases, such as Alzheimer?s Disease. The monoclonal antibody CTD110.6 is a valuable tool for the study of O-GlcNAc. This antibody specifically recognizes the modification on a wide variety of proteins in a manner that is analogous to the widely used antibodies to protein phosphorylation.
Looking for Partners:
Researchers interested in transcription, diabetes, tumor suppressors , oncogenes or cytoskeletal proteins. Potentially useful as a diagnostic tool, especially in diabetes and Alzheimer's Disease.
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Direct Link:
https://jhu.technologypublisher.com/technology/18720
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Category(s):
Clinical and Disease Specializations, Clinical and Disease Specializations > Diabetes, Clinical and Disease Specializations > Metabolic Diseases, Clinical and Disease Specializations > Neurology, Clinical and Disease Specializations > Oncology, Technology Classifications > Research Tools > Antibodies, Technology Classifications > Therapeutic Modalities > Antibodies, Technology Classifications > Therapeutic Modalities > Biologics, Technology Classifications > Research Tools, Technology Classifications > Therapeutic Modalities,
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For Information, Contact:
Michael Woods
mwoods19@jh.edu
410-614-0300
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