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A Method for Non-invasive Cerebral and Systemic Cooling and Neuroprotection

Case ID:
C10570
Disclosure Date:
12/2/2008
C10570: A Method for Non-invasive Cerebral and Systemic Cooling and Neuroprotection
Technical Details:
A method for achieving cerebral cooling by expansion of a gas delivered into the patients’ nasopharynx is described. The gas is compressed and delivered via a nasal catheter in to the nasopharnx. The gas is allowed to exit via several openings in the catheter inside the nasal cavity. Expanding gas cools the nasopharynx and the air in the para nasal sinuses and convective cooling of the brain stem is achieved. The gas may be an anesthetic (eg., N20, Xenon etc) that additionally may have neuroprotective chemical properties, and systemic effects which may additionally promote systemic cooling. The nasal catheter may have additional lumens to regulate pressure and temperature within the nasal cavity to allow decompression and sufficient cooling. The method described can also be used in other organ systems in particular the pulmonary bed to achieve cooling and neuroprotection.
Patent Information:
Title App Type Country Serial No. Patent No. File Date Issued Date Expire Date Patent Status
A Method for Non-invasive Cerebral and Systemic Cooling and Neuroprotection PCT: Patent Cooperation Treaty China 201180009724.7 ZL201180009724.7 2/16/2011 8/10/2016 2/16/2031 Granted
A Method for Non-invasive Cerebral and Systemic Cooling and Neuroprotection PCT: Patent Cooperation Treaty European Patent Office 11745187.2 2536343 2/16/2011 11/23/2022 2/16/2031 Granted
A Method for Non-invasive Cerebral and Systemic Cooling and Neuroprotection PCT: Patent Cooperation Treaty Canada 2,789,466 2789466 2/16/2011 3/29/2022 2/16/2031 Granted
A Method for Non-invasive Cerebral and Systemic Cooling and Neuroprotection PCT: Patent Cooperation Treaty Austria 11745187.2 2536343 2/16/2011 11/23/2022 2/16/2031 Granted
A Method for Non-invasive Cerebral and Systemic Cooling and Neuroprotection PCT: Patent Cooperation Treaty France 11745187.2 2536343 2/16/2011 11/23/2022 2/16/2031 Granted
A Method for Non-invasive Cerebral and Systemic Cooling and Neuroprotection PCT: Patent Cooperation Treaty Germany 60 2011 073 468.7 2536343 2/16/2011 11/23/2022 2/16/2031 Granted
A Method for Non-invasive Cerebral and Systemic Cooling and Neuroprotection PCT: Patent Cooperation Treaty Ireland 11745187.2 2536343 2/16/2011 11/23/2022 2/16/2031 Granted
A Method for Non-invasive Cerebral and Systemic Cooling and Neuroprotection PCT: Patent Cooperation Treaty United Kingdom 11745187.2 2536343 2/16/2011 11/23/2022 2/16/2031 Granted
A Method for Non-invasive Cerebral and Systemic Cooling and Neuroprotection DIV: Divisional Australia 2016203347 2016203347 2/16/2011 6/28/2018 2/16/2031 Granted
Method and Device for Non-invasive Anatomical and Systemic Cooling and Neuroprotection PCT: Patent Cooperation Treaty United States 13/579,370 9,629,745 1/9/2013 4/25/2017 2/16/2031 Granted
Method and Device for Non-invasive Anatomical and Systemic Cooling and Neuroprotection CIP: Continuation-in-part United States 13/751,617 9,744,071 1/28/2013 8/29/2017 10/1/2033 Granted
Method and Device for Non-invasive Anatomical and Systemic Cooling and Neuroprotection CON: Continuation United States 14/065,761 8,932,339 10/29/2013 1/13/2015 10/29/2033 Granted
METHOD AND DEVICE FOR NON-INVASIVE ANATOMICAL AND SYSTEMIC COOLING AND NEUROPROTECTION CON: Continuation United States 16/903,162 11,523,937 6/16/2020 12/13/2022 5/11/2031 Granted
METHOD AND DEVICE FOR NON-INVASIVE ANATOMICAL AND SYSTEMIC COOLING AND NEUROPROTECTION CON: Continuation United States 17/965,606 11,957,617 10/13/2022 4/16/2024 2/16/2031 Granted
METHOD AND DEVICE FOR NON-INVASIVE ANATOMICAL AND SYSTEMIC COOLING AND NEUROPROTECTION CON: Continuation United States 18/604,354   3/13/2024     Pending
Direct Link:
https://jhu.technologypublisher.com/technology/18732
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For Information, Contact:
Louis Mari
lmari3@jhu.edu
410-614-0300
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