12612 B6.129-Gria1/J; 12613 B6.129-Gria1/J; 12614 B6.129-Gria1/J; 12615 B6.129-Gria2/J; 12616 B6.129-Gria3/J; 12617 B6.129-Gria3tm2R1h/J; 12618 B6.129-Gria4/J; 12619 B6.129-Gria4tm1R1h/J

• 12612 B6.129-Grial/J

• 12613 B6.129-Grial/J

• 12614 B6.129-Grial/J

• 12615 B6.129-Gria2/J

• 12616 B6.129-Gria3/J

• 12617 B6.129-Gria3tm2Rlh/J

• 12618 B6.129-Gria4/J

• 12619 B6.129-Gria4tmlRlh/J

Lee HK, Takamiya K, He K, Song L, Huganir RL. Specific roles of AMPA receptor subunit GluR1 (GluA1) phosphorylation sites in regulating synaptic plasticity in the CA1 region of hippocampus. J Neurophysiol. 2010 Jan;103(1):479-89. Epub 2009 Nov 11.

Technical Details:

Mouse models can make essential contributions to our understanding of the cause, prevention and treatment of disease. This invention provides mouse strains for studying addiction and eating disorders, synaptic plasticity, further characterizing the role of Grial, or for further characterization of synaptic function of the following genes: Gria2, Gria3, Gria4.