Non-invasive brain stimulation method for improvement of motor symptoms in Parkinsons Disease

Case ID:
C13031
Disclosure Date:
4/22/2014

Non-Invasive Treatment to Improve Motor Function for Parkinson’s Disease

JHU REF: C13031

 

Invention Novelty: A minimally invasive method and device for symptom management and treatment of early stage Parkinson's disease (PD) using transcranial direct current stimulation (tDCS).

 

Value Proposition:

Current treatments for PD have known issues associated with their use including their high cost, side effects and diminishing efficacy over time.  One method for treatment is deep brain stimulation which carries significant surgical risks and costs.  Transcranial direct current stimulation (tDCS) offers a low-cost, minimally invasive approach to brain stimulation that allows patients to remain on their current medications.  Additional benefits include:

-       Improved motor performance post-treatment

-       Effective in patients in conjunction with medication and as a stand-alone therapy

-       Non-invasive approach

 

Technical Details:

Johns Hopkins researchers have identified an approach using tDCS to improve the effectiveness of current treatments.  tDCS is a non-invasive procedure in which direct current is passed through electrodes placed on the head and localized using MRI, transcranial magnetic stimulation (TMS), or EEG.  The inventors have identified a novel protocol for administering tDCS to patients that allows patients to remain on their current medication with demonstrated efficacy in improving motor symptoms over drug alone.

 

Looking for Partners: To develop and commercialize the technology as a method and device in the application of tDCS to those with Parkinson’s disease and other neuromuscular disorders.

 

Stage of Development: Prototype

 

Data Availability: Prototype, Clinical Study

 

Patent Status: Pending

 

Publication(s)/Associated Cases: Not at this time

Patent Information:
Title App Type Country Serial No. Patent No. File Date Issued Date Expire Date Patent Status
Non-invasive brain stimulation method for improvement of motor symptoms in Parkinsons Disease PCT: Patent Cooperation Treaty United States 15/506,538 10,518,092 2/24/2017 12/31/2019 10/28/2035 Granted
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For Information, Contact:
Lisa Schwier
lschwie2@jhu.edu
410-614-0300
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