C12135 Efficient Computation OCT for Real-time 3D and 4D Imaging
Invention novelty: The current invention is a method for real-time visualization of Doppler OCT.
Value Proposition:
Traditional Doppler information processing is computationally expensive, and hence time consuming. There is a need to reduce the computation requirements and speed up the workflow of such procedures.
The proposed invention uses a new processing algorithm and multiple graphics processing units (GPUs) to greatly reduce the computation time of traditional Doppler information processing. It is the first reported online method to provide volume information for the flow in the area of interest. It has the following advantages:
- Real-time system could act as an intraoperative and postoperative imaging modality to improve surgical outcome
- Fast data processing speed to provide simultaneous 3D and 4D flow and structure information
- Improved signal-to-noise ratio
Technical Details:
Johns Hopkins researchers have developed a real-time 3D (2D cross-sectional image plus time) and 4D (3D volume plus time) phase-resolved Doppler OCT (PRDOCT) imaging based on configuration of dual graphics processing units. A GPU-accelerated phase-resolving processing algorithm was developed and implemented. A structural image intensity-based thresholding mask and average window method improve the signal-to-noise ratio of the Doppler phase image. A 2D simultaneous display of the structure and Doppler flow images was presented at a frame rate of 70 fps with an image size of 1000x1024 (XXZ) pixels. A 3D volume rendering of tissue structure and flow images—each with a size of 512x512 pixels—was presented 649 milliseconds after every volume scanning cycle with a volume size of 500x256x512 (XxYxZ) voxels and an acquisition time window of only 3.7 seconds. To the best of our knowledge, this is the first time that an online, simultaneous structure and Doppler flow volume visualization has been achieved. Maximum system processing speed was measured to be 249,000 A-scans per second with each A-scan size of 2048 pixels.
Looking for Partners: To develop and commercialize the technology as a method of real time Doppler OCT visualization.
Stage of Development: Pre-Clinical
Data Availability: Under CDA/NDA
Patent Status: Pending
Publication(s)/Associated Cases: Not available at this time
Categories: Medical Imaging
Keywords: real-time, OCT, Doppler, volume rendering, GPU,
