C11284 Method to Measure Wall Motion and Wall Thickness Using Contrast Enhanced Fluoroscopy
Background
Most invasive angiograms end in the measurement of heart function by performing a ventriculogram. Performance of left ventriculography (LVG) requires additional contrast agent (about 30 – 40ml), catheter and time. Scientists at Johns Hopkins have developed a novel method for visualization of the left ventricular myocardium following a contrast injection for a coronary angiogram.
Applications
Technology developed will allow
- Display of global and regional wall motion
- Calculation of LV ejection fraction by measuring inner wall motion
- Wall thickness
- Perfusion map image that includes effect of myocardium thickness
- Fusion with fluoroscopy to easily recognize catheter position in LV
- Method can be used to target Intracardiac therapies delivered by intra-arterial and intra-venous catheters
Advantages
- Improve patient safety by avoiding the need to cross the aortic valve to place a catheter in the left ventricle
- Avoid arrhythmias that occur with this procedure
- Avoids risk of stroke
- No additional nephrotoxic contrast will be needed to measure LV function
Stage of Development: Preclinical
Technology: This innovation is a novel method for visualization of the left ventricular myocardium.
Protection Status: Patent pending
Licensing Status: Available for licensing
Keywords
Diagnosis, Imaging
