Detecting Osteoporosis Using Photoacoustic Spectroscopy

Case ID:
C12808

C12808 Photoacoustic Osteoarthritis Diagnosis

 

Invention Novelty: A novel method that performs early detection of osteoarthritis through a low-cost, portable photoacoustic imaging system.

 

Value Proposition: Osteoporosis affects 15 million Americans, with an additional 30 million considered at risk for the disease. The current standard of care for osteoarthritis detection includes radiological imaging methods such as x-ray and computed tomography. However due to radiographic limitations, the value of a non-radiological imaging technique is high. Other techniques such as MRI and PET are expensive, and therefore osteoporosis is seldom diagnosed in the early stages. Photoacoustic imaging can be used as a low-cost, portable technology for the early detection of osteoporosis. This technology is sensitive to the architectural and mechanical features of bone, and therefore is capable of detecting osteoarthritis in patients. The advantages of this system include:

-       A single portable system that has a number of degrees of freedom for various regions of interest

-       The ability to introduce the light source interventionally, for deep bone imaging

-       The ability to integrate the system with robotic arms and systems

 

Technical Details: Johns Hopkins researchers have created a novel device that can detect osteoarthritis in its early stages using photoacoustic imaging. The system utilizes an excitation source to generate resultant waves in the patient. The waves propagate through the patient, and the data is acquired by an ultrasound probe. When used to detect bone density, a decrease in photoacoustic intensity spectrum is seen in osteoporotic bone compared to normal bone. This information can then be relayed to the physician for further diagnosis.

 

Looking for Partners: To develop and commercialize the technology as a photoacoustic diagnostic system for the diagnosis of osteoporosis and arthritis in its early stages

 

Stage of Development: Pre-Clinical

 

Data Availability: Under CDA/NDA

 

Patent Status: Pending

 

Publication(s)/Associated Cases: Not at this time

  

Categories: Photoacoustic Imaging

Keywords: Osteoporosis, osteoarthritis, arthritis, photoacoustic imaging, ultrasound, diagnostics, bone density

 

Patent Information:
Title App Type Country Serial No. Patent No. File Date Issued Date Expire Date Patent Status
SYSTEMS AND METHODS FOR REAL-TIME TRACKING OF PHOTOACOUSTIC SENSING ORD: Ordinary Utility United States 14/561,087 9,723,995 12/4/2014 8/8/2017 5/19/2035 Granted
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For Information, Contact:
Lisa Schwier
lschwie2@jhu.edu
410-614-0300
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