Method for Preview of Low-dose X-ray Projection and Tomographic Images
JHU REF: C12935
Invention Novelty:
Researchers at Johns Hopkins University have developed a novel method for generating sets of low-dose preview images from Cone Beam CT (CBCT) scans that were performed at a higher dose. Though existing technology can inject noise into an image, the invention is the first to inject calibrated noise into an image and attain a set of low dose preview images from a high quality image attained at a nominal intensity.
Value Proposition:
The technology is the first technology to inject calibrated noise into images attained at a nominal intensity in order to predict lower quality images attained at lower radiation intensity. By predicting image depreciation due to a reduced dose and thus higher noise, a clinician can determine the lower bound of image quality needed for a procedure and can reduce excessive radiation exposure.
The technology addresses an industry stated need of reducing radiation exposure from CT scans. Makers of CT systems state needs in intensity reduction in both 1-2 and 3-5 year planning windows, while the American Journal of Roentgenology suggests that radiation doses could be reduced by 32%. As CT continues to find new applications, such as in lung cancer screening, where it is the first diagnostic screening to reduce mortality (~20%) of lung cancer, the CT industry growth is expected. The invention could be used in conjunction with existing CT equipment to lower radiological dose, so tailored to a procedure.
Technical Details:
The technology is an algorithm that injects calibrated noise into images attained at a nominal dose. The injected noise simulates lower quality images from a high quality image by injecting calibrated noise into an image attained at a higher radiation dose. Low quality preview images allow a clinician to determine the lower bound of image quality necessary for a procedure and thus allows for imaging to be conducted at lower radiation intensity.
Looking for Partners: To integrate this novel algorithm with existing CT and Cone Beam CT (CBCT) systems
Stage of Development: Prototype
Data Availability: Prototype
Patent Status: Provisional
Publication(s)/Associated Cases: Adam S. Wang et al. (2014), “Low-Dose Preview for Patient- and Task-Specific Minimum-Dose Cone-Beam CT” unpublished presentation at Johns Hopkins
Categories: Radiology, Diagnostics
Keywords: Radiology, Low Dose Preview, CT, Cone Beam CT scan
