DPL: Packaging Cell Line For Diphtheria Toxin Expressing Non-replicating Adenovirus

Case ID:

C04048

The invention provides a packaging cell line for production of diphtheria toxin (DT) expressing, non-replicating adenovirus for use in suicide gene therapy of cancer cells, as well as production of immunotoxins. Also provided are methods for producing diphtheria toxin (DT) expressing, non-replicating adenovirus, methods for producing immunotoxins, and adenovirus and immunotoxins produced by those methods. Further provided are methods for making a cell resistant to diphtheria toxin.

Patent Information:

Title	App Type	Country	Serial No.	Patent No.	File Date	Issued Date	Expire Date	Patent Status
Packaging Cell Line for Diphtheria Toxin Expressing Non-Replicating Adenovirus	PCT: Patent Cooperation Treaty	United States	10/510,592	7,582,290	8/17/2005	9/1/2009	4/8/2023	Granted

Direct Link:

https://jhu.technologypublisher.com/technology/24200

Inventors:

Category(s):

Clinical and Disease Specializations, Clinical and Disease Specializations > Infectious Diseases, Technology Classifications > Research Tools > Cell Lines, Technology Classifications > Research Tools > Human Cell Lines, Technology Classifications > Research Tools > Viruses, Technology Classifications > Research Tools, Clinical and Disease Specializations > Oncology, Technology Classifications > Therapeutic Modalities > Peptides,

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For Information, Contact:

Vera Sampels

vsampel2@jhu.edu

410-614-0300

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