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An Imaging Toolbox for Guiding Cardiac Resynchronization Therapy Implantation from Patient-Specific Computed Tomography and Body Surface Potential Mapping Data
Case ID:
C12672
Report of Invention:
8/14/2013
Web Published:
2/24/2017
Guiding Cardiac Resynchronization Therapy Implantation
JHU REF: C12672
Invention novelty:
This method is for evaluating cardiac properties from Computed Tomography (CT) scan combined with Body Surface Potential Mapping (BSPM).
Value Proposition:
Heart failure is a major public health problem in the United States that affects 5 million people and contributes to an increasing number of hospitalizations and deaths. Advances in techniques delivered during cardiac resynchronization therapy (CRT) have provided non-pharmacological options for patients with moderate to severe heart failure. However, the non-response rate among patients who receive CRT devices remains high in the 30-40% range. The present technology is a method that would allow integration of information obtained non-invasively from standard CT and ECG exams which can be performed prior to CRT device implantation for planning and guiding the procedure. Other advantages include:
planning and guiding implantation more quickly, within minutes to hours
minimal user input is required decreasing the rate of human error
Technical Details:
Johns Hopkins researchers have developed a method for quantitative assessment and estimation of mechanical contraction patterns, tissue viability and venous anatomy from Computed Tomography (CT) scan combined with electrical activation patterns obtained from Body Surface Potential Mapping (BSPM) which can be acquired non-invasively during routine scans. In order to guide implantation of cardiac resynchronization therapy (CRT) pacing devices, the combined CT-BSPM method is capable of integrating electrical, mechanical, structural information about cardiac structure and function. The method recommends cardiac segments and routes to optimize implantation of the device. In addition, the method generates regional electro-mechanical properties overlaid with cardiac venous distribution and scar tissue.
Looking for Partners:
To develop and commercialize the technology as data acquisition hardware and ECG recording apparatus to streamline the collection of the electrical data
Stage of Development
:
Pre-Clinical
Data Availability:
Under CDA/NDA
Patent Status:
Pending
Publication(s)/Associated Cases:
Not at this time
Patent Information:
Title
App Type
Country
Serial No.
Patent No.
File Date
Issued Date
Expire Date
Patent Status
An Imaging Toolbox for Guiding Cardiac Resynchronization Therapy Implantation from Patient-Specific Imaging and d Body Surface Potential Mapping Data
PCT: Patent Cooperation Treaty
United States
15/310,580
10,959,618
11/11/2016
3/30/2021
6/2/2037
Granted
Direct Link:
https://jhu.technologypublisher.com/technology/24301
Inventors:
Category(s):
Clinical and Disease Specializations, Clinical and Disease Specializations > Cardiovascular > Congestive Heart Failure, Technology Classifications > Computers, Electronics & Software > Image Processing & Analysis, Technology Classifications > Medical Devices > Imaging, Technology Classifications > Medical Devices > Therapeutic Devices, Clinical and Disease Specializations > Cardiovascular, Technology Classifications > Computers, Electronics & Software, Technology Classifications > Medical Devices,
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For Information, Contact:
Louis Mari
lmari3@jhu.edu
410-614-0300
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