A Rabbit Polyclonal Antibodies Specific for S113 and S117 Phosphorylated Sam68 (Src-associated substrate in mitosis of 68 kDa), an RNA-binding Protein with Multi-functions in the Cell

TITLE

rabbit polyclonal antibodies specific for S113 and S117 phosphorylated Sam68 (Src-Associated substrate in Mitosis of 68 kDa)

 

CASE NUMBER

C13182

 

ABSTRACT

An rabbit polyclonal antibodies specific for S113 and S117 phosphorylated Sam68 generated and affinity purified using the peptide NH2-CAEKD(Sp)LDP(Sp)FTH-COOH by Primm (Cambridge, MA).

 

FEATURES

The research recent study (Fu K. et al. Nature Communications, 2013) demonstrated that Sam68 is a novel substrate of IKKalpha kinase, and during T cell receptor engagement-induced activation signaling, Sam68 was phosphorylated by IKKalpha at S113 and S117 residues. This is the first description of serine/threonine phosphorylation of Sam68 in pathophysiological settings.

 

DESCRIPTION DETAIL

The rabbit polyclonal antibodies specific for S113 and S117 phosphorylated Sam68 would be useful to examine the specific post-translational modifications of Sam68 under various pathophysiological settings.

 

PI: Fengyi Wan

 

ASSOCIATED PUBLICATION

Nat Commun. 2013;4:1909

 

CONTACT INFORMATION

Carole Burns

Senior Licensing Associate

410-502-5581

cburns21@jhu.edu

 

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