Biocompatible "smart" nanogels as carriers for hydrophobic drugs

Case ID:

C05024

The present invention involves a biocompatible nanogel composition for the delivery of hydrophobic substances that are not readily soluble in organic solvents. These nanogels have been designed to contain hydrophobic cores which encapsulate the insoluble molecules, and a hydrophilic shell which allows long term systemic circulation. The nanogels constitute discrete particles that are less than 100 nm in size. The compositions are non-toxic and non-antigenic, and are suitable for systemic administration by injectable, oral, ophthalmic, or pulmonary means. Furthermore, the surface of the nanogels can be functionalized for targeted delivery.

Patent Information:

Title	App Type	Country	Serial No.	Patent No.	File Date	Issued Date	Expire Date	Patent Status
Water-Dispersible oral, Parenteral, and Topical Formulations for Poorly Water Soluble Drugs Using Smart Polymeric Nanoparticles	PCT: Patent Cooperation Treaty	United States	11/867,918	8,313,777	10/5/2007	11/20/2012	9/20/2031	Granted
Water-Dispersible oral, Parenteral, and Topical Formulations for Poorly Water Soluble Drugs Using Smart Polymeric Nanoparticles	CON: Continuation	United States	13/650,273	8,715,741	10/12/2012	5/6/2014	10/5/2027	Granted

Direct Link:

https://jhu.technologypublisher.com/technology/24629

Inventors:

Category(s):

Technology Classifications > Therapeutic Modalities > Therapeutic Delivery Platforms, Technology Classifications > Therapeutic Modalities,

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For Information, Contact:

Mohit Ganguly

mgangul1@jh.edu

410-614-0300

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