Three-dimensional Vascular Network Assembly from Diabetic Patient-derived Induced Pluripotent Stem Cells

Case ID:

C13526

In diabetics, hyperglycemia results in deficient endothelial progenitors and cells, leading to cardiovascular complications. We aim to engineer three-dimensional (3D) vascular networks in synthetic hydrogels from type-1 diabetes (T1D) patient-derived human induced pluripotent stem cells (hiPSCs), thus serving as a transformative autologous vascular therapy for diabetic patients.

Patent Information:

Title	App Type	Country	Serial No.	Patent No.	File Date	Issued Date	Expire Date	Patent Status
Three-dimensional Vascular Network Assembly from Diabetic Patient-derived Induced Pluripotent Stem Cells	PCT: Patent Cooperation Treaty	United States	15/746,477	11,332,717	1/22/2018	5/17/2022	1/1/2037	Granted

Direct Link:

https://jhu.technologypublisher.com/technology/24819

Inventors:

Category(s):

Clinical and Disease Specializations, Clinical and Disease Specializations > Diabetes, Clinical and Disease Specializations > Metabolic Diseases, Technology Classifications > Therapeutic Modalities, Technology Classifications > Therapeutic Modalities > Biologics, Technology Classifications > Therapeutic Modalities > Cell Therapies, Technology Classifications > Therapeutic Modalities > Stem Cells,

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For Information, Contact:

Heather Curran

hpretty2@jhu.edu

410-614-0300

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