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CADENCE Balloon Shunt
Case ID:
C13946
Report of Invention:
12/22/2015
Web Published:
3/21/2017
CADENCE is a novel, patented treatment platform that functions to alter cerebrospinal fluid (CSF) flow, increase cerebral blood flow (CBF), and modulate the intracranial pressure (ICP) wave through natural cardiac-induced dynamics. CADENCE can be visualized as an intra-aortic balloon pump for the brain and therefore functionally very distinct from a CSF shunt. For patients with hydrocephalus, the current method of passive shunting drains CSF and reduces ICP, but it does not directly address CBF. CADENCE’s ability to alter CSF flow, increase CBF, and modulate ICP addresses clinical unmet needs that passive shunting cannot address. As an entry point for potentially treating a vast array of diseases associated with increased levels of CSF the inventors have shown preliminary proof-of-concept that the CADENCE system can actively and controllably improve CSF pressure pulsation and CBF in NPH animal models and normal brains.
Patent Information:
Title
App Type
Country
Serial No.
Patent No.
File Date
Issued Date
Expire Date
Patent Status
SYSTEMS AND METHODS FOR CONTROLLING A VOLUME OF FLUID WITHIN A PORTION OF A PATIENT'S BODY
PCT: Patent Cooperation Treaty
United States
15/999,842
12,239,426
8/20/2018
3/4/2025
11/19/2037
Pending
Direct Link:
https://jhu.technologypublisher.com/technology/24949
Inventors:
Category(s):
Clinical and Disease Specializations, Clinical and Disease Specializations > Neurology > Stroke, Technology Classifications > Medical Devices > Therapeutic Devices, Technology Classifications > Medical Devices, Clinical and Disease Specializations > Neurology,
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For Information, Contact:
Louis Mari
lmari3@jhu.edu
410-614-0300
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