RiBns for Rhomboid Proteases

Case ID:

C14194

This invention describes a method for creating novel, inhibitors of desired bacterial rhomboid proteases (RhP), and applies this method to produce potent antibiotics. The value proposition is very high providing a means of identifying and creating novel, specific bacterial Rhp inhibitors (antibiotics) with a novel mechanism of action to prevent/overcome drug resistance.

Patent Information:

Title	App Type	Country	Serial No.	Patent No.	File Date	Issued Date	Expire Date	Patent Status
PEPTIDES HAVING TETRAHEDRAL MIMICKING GROUPS AS INHIBITORS OF RHOMBOID PROTEASES	PCT: Patent Cooperation Treaty	United States	16/307,068	11,518,783	12/4/2018	12/6/2022	6/6/2037	Granted

Direct Link:

https://jhu.technologypublisher.com/technology/25123

Inventors:

Category(s):

Clinical and Disease Specializations, Clinical and Disease Specializations > Infectious Diseases > Malaria, Clinical and Disease Specializations > Infectious Diseases > Parasitic Infections, Technology Classifications > Therapeutic Modalities > Biologics, Technology Classifications > Therapeutic Modalities > Peptides, Clinical and Disease Specializations > Infectious Diseases, Technology Classifications > Therapeutic Modalities, Clinical and Disease Specializations > Infectious Diseases > Bacterial Infections, Technology Classifications > Therapeutic Modalities > Small Molecules,

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For Information, Contact:

Mohit Ganguly

mgangul1@jh.edu

410-614-0300

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