HIF-1

Case ID:

C09970

The purified and characterization of hypoxia-inducible factor 1 (HIF-1) is described. HIF-1 is composed of subunits HIF-1 and HIF-1 . Purified HIF-1 polypeptide, its amino acid sequence and polynucleotide sequence are provided. A HIF-1 variant that dimerizes to HIF-1 producing a nonfunctional HIF-1 complex is described. Methods for the prevention and treatment of hypoxia-related disorders are provided.

Direct Link:

https://jhu.technologypublisher.com/technology/36454

Inventors:

Category(s):

Clinical and Disease Specializations, Clinical and Disease Specializations > Cardiovascular, Technology Classifications > Therapeutic Modalities, Technology Classifications > Therapeutic Modalities > Biologics, Technology Classifications > Therapeutic Modalities > Peptides,

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For Information, Contact:

Jeanine Pennington

jpennin5@jhmi.edu

410-614-0300

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