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Novel Cardiac Implants and Associated Catheter Systems to Treat Malfunctioning Cardiac Valves
Case ID:
C14624
Report of Invention:
2/21/2017
Web Published:
10/9/2019
Unmet Need
A common heart disorder seen in thousands of patients per year is regurgitation, a condition where the heart’s valves do not close sufficiently during systolic contraction, allowing for blood to leak from the ventricle into the atrium. This leakage varies from moderate to severe, and at high levels can put the patient at risk of many other heart disorders such as frailty and pulmonary hypertension. There have been many challenges in the development of a technology to address this issue due to the structural complexity of the heart’s valves, as well as the intricacies of the heart’s contractive mechanism. It is critical to find an effective and noninvasive treatment for regurgitation as an early preventative measure for many other heart diseases.
Technology Overview
This invention is a set of novel implants and their associated catheter systems that will be able to treat cardiac valve regurgitation disease. This system can be inserted via catheters, providing a minimally invasive method of implant insertion that lowers the cost from a typical open heart surgery. The technology acts as a detachable plug that works in cooperation with the leaflets of the heart valves, improving their coaptation during rhythmic contractions. This method improves on already existing transcatheter systems by offering self-centering capabilities, reducing drag and friction, and allowing for easy replacement if any complications are to arise post-insertion. In addition, the system is patient specific and offers a variety of models to optimize its application.
Stage of Development
Early proof of concept/pre-clinical stage
Publications
ME Guerrero, et al. “Transcatheter Mitral Valve Replacement Therapies.” Am. College of Cardiology (April 28, 2017).
Patent Information:
Title
App Type
Country
Serial No.
Patent No.
File Date
Issued Date
Expire Date
Patent Status
System and Methods of Treating Malfunctioning Cardiac Valves
PCT: Patent Cooperation Treaty
European Patent Office
18806946.2
5/25/2018
Pending
SYSTEMS AND METHODS OF TREATING MALFUNCTIONING CARDIAC VALVES
PCT: Patent Cooperation Treaty
United States
16/617,044
11,219,522
11/27/2019
1/11/2022
8/3/2038
Granted
Direct Link:
https://jhu.technologypublisher.com/technology/36517
Inventors:
Category(s):
Clinical and Disease Specializations, Clinical and Disease Specializations > Cardiovascular, Technology Classifications > Medical Devices > Surgical, Technology Classifications > Medical Devices > Therapeutic Devices, Technology Classifications > Medical Devices,
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For Information, Contact:
Lisa Schwier
lschwie2@jhu.edu
410-614-0300
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