Gene Expression Profile Determination and Prognostication in Uveal Melanoma Using Artificial Intelligence

Case ID:
C15610
Disclosure Date:
12/5/2018

Prognostication in Uveal Melanoma Using Artificial Intelligence

 

Disclosure Date:

12/05/2018

 

Description:

 

Unmet Need

Uveal melanoma is the most common primary intraocular malignancy in adults. According to the University of Michigan W. K. Kellogg Eye Center, there are 5 to 6 uveal melanoma cases per million people per year. For people over the age of 50, incidence rates increase to 21 cases per million per year. Providing an accurate prognosis for a patient with uveal melanoma is key to identifying the proper corresponding care. Currently, a prognosis can be made after a fine needle biopsy of the melanoma is sent for a gene expression profile (GEP) test. However, the current gold standard for establishing prognosis has its drawbacks. First, the GEP test is only available in the United States and could cost thousands of dollars. Second, a small portion of GEP class 1 patients could still have unexpected poor outcomes.

 

Technology Overview

Johns Hopkins researchers have developed a novel survival prediction tool that utilizes deep-learning-based image analysis.   

 

Stage of Development

Computational process in development.

 

Publications

N/A

 

Patent Information:
Title App Type Country Serial No. Patent No. File Date Issued Date Expire Date Patent Status
METHODS AND RELATED ASPECTS FOR OCULAR PATHOLOGY DECTECTION PCT: Patent Cooperation Treaty United States 18/001,992   12/15/2022     Pending
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For Information, Contact:
Mark Maloney
dmalon11@jhu.edu
410-614-0300
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