Inventor(s): Lorraine Brando, Alvaro Ordonez, Robert Yolken, Sanjay Jain
Unmet Need
COVID-19 is a worldwide problem, and infection rates continue to rise. Therefore, more therapies and prophylactics are urgently needed to suppress the rise of confirmed cases and reduce the mortality rate.
Technology Overview
Johns Hopkins researchers have invented a method to prevent and treat COVID-19. They proposed the use of sulforaphane (SF), a natural compound found in cruciferous vegetables (i.e. broccoli, kale), for COVID-19 prevention and treatment. Their in vitro experiments showed that SF inhibits SARS-CoV-2 replication, demonstrating the potential of SF to be a relatively cheap and widely available prophylactic and therapeutic against COVID-19.
Stage of Development
This technology is under pre-clinical development.
publication:
https://www.biorxiv.org/content/10.1101/2021.03.25.437060v1
https://www.nature.com/articles/d41586-022-01923-5