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Non-invasive Left Ventricular End Diastolic Pressure (LVEDP) Measurement for In-hospital, Outpatient and Home Diagnostic Monitoring
Case ID:
C13576
Report of Invention:
4/27/2015
Web Published:
8/12/2021
Unmet Need
Both physicians and surgeons rely heavily on the cardiac chamber pressures, especially that in the left ventricle, to assess the fluid volume status of patients and heart function pre and post procedures in the in-hospital setting, outpatient clinics or when patients are at their home. Current methodologies are either invasive in nature with associated complications or non-suitability for specific patient types, or they allow only measurement of surrogate parameters in lieu of LVEDP.
Technology Overview
This disclosure presents a novel approach of non-invasively establishing the LVEDP by using:
1) Specific hemodynamic relationships
2) Measurement techniques and systems to measure key parameters
3) Algorithmic approach to use the measured parameters and hemodynamic relationships to derive the LVEDP.
Stage of Development
Both animal studies (in adult pigs) and retrospective analysis of human catheterization data was performed to validate the algorithm.
Publication(s)
Patent Information:
Title
App Type
Country
Serial No.
Patent No.
File Date
Issued Date
Expire Date
Patent Status
Non-invasive Left ventricular End Diastolic Pressure (LVEDP) Measurement for In-hospital, Outpatient and Home Diagnostic Monitoring for Patients with Various Disease States
PCT: Patent Cooperation Treaty
United States
15/571,771
10,729,337
11/3/2017
8/4/2020
12/12/2036
Granted
Direct Link:
https://jhu.technologypublisher.com/technology/44659
Inventors:
Category(s):
Technology Classifications > Diagnostics > In Vivo Diagnostics, Technology Classifications > Diagnostics,
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For Information, Contact:
Lisa Schwier
lschwie2@jhu.edu
410-614-0300
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