Unmet Need
Sudden cardiac death is the leading cause of mortality in patients with chronic heart failure. However, there isn’t a standard method of assessing risk for SCDs, which is necessary for early prevention (e.g. through the implantation of a cardioverter defibrillator).
Technology Overview
The QT Variability index, measured through an electrocardiogram, is a predictor of sudden cardiac deaths. The invention is the novel use of certain respiratory measures and drug combinations to predict high QTVI, which indicates a high risk of cardiovascular events and can be used to predict risk of SCD in a clinical setting.
Stage of Development
Proof of Concept. The initial results need to be expanded in order to validate the QTVI as a regular screening tool in clinic.
Publications
N/A