Unmet Need
Digital subtraction angiography (DSA) is a commonly used x-ray technique in interventional radiology to visualize blood vessels. Two images are acquired, one with administration of iodine contrast in blood vessels and one without (non-contrast), and the subtraction of the two images yields a clear 2-dimensional (2D) projection of the vasculature with the surrounding anatomy extinguished digitally from the image. However, the subtraction assumes that no motion has occurred between the two images, while in fact, voluntary and involuntary motion is common between acquisitions. This results in artifacts in the DSA images that diminish the visibility of the vasculature and may require multiple takes. Therefore, there is a need for a method to reduce motion-induced artifacts in DSAs.
Technology Overview
Inventors at Johns Hopkins have developed a method called 2D motion compensation (2D MoCo) for reduction of motion artifacts in 2D DSA. For the non-contrast image, this novel method employs a 3-dimensional image of the patient instead, from which a 2D image is generated via 3D2D image registration. This mitigates the impact of patient motion on the quality of the generated DSA image.
Stage of Development
Preliminary testing has been conducted.
Patent
N/A
Publication
