Three Material Decomposition using a Triple-Layer Flat-Panel Detector
Report of Invention:
8/16/2022
Value Proposition: - Method for direct, real-time visualization of bone, water, and iodine contrast agents.
- Allows for better visualization of moving structures; reduces imaging artifacts induced by motion (i.e. beating heart)
Technology Description - Researchers at Johns Hopkins have developed a method for fast processing of data acquired using a triple-layer flat-panel detector (TL-FPD) for enhanced visualization and interpretation of radiographic or fluoroscopy images.
- This technology includes a machine learning model for decomposition of imaging data into bone, water, or iodine.
Unmet Need - Current methods for standard radiography and fluoroscopy presents overlapping anatomy, which obsures visualization of critical features. Additionally, contrast agent is not sufficient
- Spectral radiography acquisition via dual-energy imaging are unable to fully separate iodine contrast agents from calcium.
- Additionally, current contrast visualization methods, such as digital subtraction angiography (DSA), are sensitive to motion and can lead to artifacts that confound image processing.
- Triple layer detector is a promising acquistion strategy to address these issues but requires an accurate, real-time (for angiography applications) processing algorithm for material decomposition
Stage of Development - Machine-learning model for image processing was developed for fast, accurate material decomposition of data acquired with a triple layer flat panel detector
- Looking for partners to commercialize the technology for integration into radiographic or fluoroscopy-based diagnostic and interventional imaging.
Data Availability - Data available upon request.
Publication N/A
Patent Information:
Title |
App Type |
Country |
Serial No. |
Patent No. |
File Date |
Issued Date |
Expire Date |
Patent Status |
MACHINE LEARNING SYSTEMS AND RELATED ASPECTS FOR THREE MATERIAL DECOMPOSITION USING A TRIPLE-LAYER FLAT-PANEL DETECTOR |
PCT: Patent Cooperation Treaty |
PCT |
PCT/US2023/035371 |
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10/18/2023 |
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Pending |
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Inventors:
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