Value Proposition
· Optimized Imaging Framework: Utilizes an analytical radial synthetic aperture focusing (rSAF) approach to provide the highest possible spatial resolution and image quality while minimizing grating lobe artifacts
· Transformable Radius: Allows the transducer to contract during insertion for improved accessibility and expand during scanning for optimized imaging
· Patient Comfort: Enhances patient comfort by reducing the transducer diameter during insertion
· Broad Applications: Supports diverse clinical use, including transrectal and intravascular imaging
Unmet Need
· The global transrectal ultrasound (TRUS) market is projected to reach $371.3 million by 2030 (Fortune Business Insights). TRUS demand is largely driven by prostate biopsies. There are approximately one million prostate biopsies performed annually in the US (Cleveland Clinic).
· Current TRUS devices use small transducers to reduce pain but provide suboptimal imaging quality, while larger transducers improve imaging but cause more pain and produce grating lobe artifacts.
· Thus, there exists a strong need for developing a solution that reduces patient pain while optimizing image quality.
Technology Description
· Current transrectal imaging methods cause patient discomfort or deliver suboptimal image quality.
· Researchers at Johns Hopkins have developed a transrectal ultrasound device that reduces discomfort while providing the highest possible spatial resolution and image quality. The device features a transformable radius and an analytical radial synthetic aperture focusing (rSAF) framework.
· The transformable radius allows the transducer to contract during insertion for easier access and expand during scanning to optimize imaging.
· The analytical rSAF solution maximizes spatial resolution and image quality while reducing grating lobe artifacts.
Stage of Development
· As of 8/23/2021: The theoretical foundation had been established and validated with extensive simulations. Efforts at the time were focused on prototype development and preclinical and clinical validations.
Data Availability
· Data available upon request.
Publication
Hyunwoo Song, Jeeun Kang, Emad M. Boctor. An analytical approach to optimize radial synthetic aperture focusing for volumetric transrectal ultrasound imaging. TechRxiv. June 25, 2021. DOI: 10.36227/techrxiv.14825823.v1