#C16445
Unmet Need
This invention addresses the long time and need for a lab setting in the production of 18F-FDS tracers for PET scans. Traditionally, 18F-FDS production takes at least 30 minutes and needs precise temperature control, limiting its use in imaging clinics in low resource areas.
Technology Overview
Researchers at Johns Hopkins University have developed a method for synthesizing 18F-FDS in under 10 minutes, at room temperature. The kit consists of a small cartridge (max. 10 cc) containing a borohydride resin (macroporous triethylammonium triethylammonium methylpolystyrene borohydride) for solid-phase reduction, attached to a Chromabond V cartridge (the same used for 18F-FDG) for purification. This will allow imaging clinics to have same day 18F-FDS imaging which is extremely valuable in identifying certain infections.
Stage of Development
The current chemical pathway has been developed, and the current efforts are focused around scaling up production to suitable human doses.
