Value Proposition
· Software metrics are aligned with established standards of care
· Focuses on prevention of postoperative AKI
· Enhances clinical decisions and patient outcomes
· Open market for AKI monitoring equipment
Unmet Need
In the United States, the average American undergoes seven surgical operations over their lifetime. Annually, at least 150,000 patients die and 1.5 million experience medical complications within 30 days after surgery. Post-operative acute kidney injury (AKI) is a highly common complication following surgery. Despite the identification of risk factors for post-operative AKI, there are currently limited monitoring platforms to evaluate these risks during surgery. The most common modifiable risk factor of kidney injury his abnormal hemodynamics; though these are recorded, they are not processed and presented to clinicians. This highlights a significant unmet need for the development of enhanced monitoring strategies to prevent the occurrence of postoperative AKI in patients.
Technology Description
Researchers at Johns Hopkins have developed an intraoperative monitor-embedded software program that tracks and summarizes the total minutes a patient’s blood pressure remains below a target threshold during surgery. The multivariable models integrated into the software are consistent with existing research, showing a linear correlation between the duration of threshold blood pressure and the incidence of postoperative AKI. This tool aims to inform clinical care decisions, thereby enhancing patient outcomes and improving the overall quality of healthcare delivery.
Stage of Development
This technology has advanced beyond the development phase, with both software and hardware fully prepared for integration into existing monitoring systems.
Data Availability
· Data available upon request.
Publication
Pending patent application
