Novel inhibitors of protein kinase signaling that are neuroprotective and have potential applicability for the treatment of glaucoma, optic nerve disease, and other forms of neurodegeneration - #2

Glaucoma is a major cause of visual loss and blindness in elderly Americans and throughout the world. One approach to treatment of glaucoma, and other optic nerve diseases as well as other neurodegenerations, is to develop neuroprotective agents that promote the survival of neurons. Through a high content screen of libraries of small molecule compounds,...

Novel Inhibitors of Protein Kinase Signaling that are Neuroprotective and have Potential Applicability for the Treatment of Glaucoma, Optic Nerve Disease, and other Forms of Neurodegeneration

Glaucoma is a major cause of visual loss and blindness in elderly Americans and throughout the world. One approach to treatment of glaucoma, and other optic nerve diseases as well as other neurodegenerations, is to develop “neuroprotective” agents that promote the survival of neurons. We have synthesized and tested a number of novel compounds, based...

A Neuroprotective Agent with Applicability to Glaucoma, Optic Nerve Diseases, and other Neurodegenerations

C10454: Known Drug found to have applicability in the area of glaucoma, optic nerve diseases, and other neurodegenerationsValue Proposition: Key Features • Provides treatment for glaucoma, other optic nerve diseases, and potentially any disease with neuronal dysfunction or loss. • Exploits an FDA approved drug, which may reduce clinical hurdles and...