Search Results - carol+greider

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Measuring Telomere Length Using Sequencing Technology

Unmet NeedTelomeres are repetitive sequences found at the end of eukaryotic chromosomes that play a key role in eukaryotic genomic stability. In humans, telomeres naturally shorten with time. Genetic disruption to telomere biology can cause dyskeratosis congenita and pulmonary fibrosis, while telomere length contributes to complex diseases such as cancer...

Published: 9/12/2025 | Inventor(s): Kayarash Karimian, Carol Greider

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Category(s): Clinical and Disease Specializations > Genetic Diseases > Dyskeratosis Congenita/Zinsser-Engman-Cole Syndrome, Clinical and Disease Specializations > Fibrosis

Assay for telomere length regulators (ADDIT Addition of de novo initiated telomeres)

INVENTION NOVELTY This invention is a new assay termed ADDIT (Addition of de novo initiated telomeres) that can rapidly identify effectors of telomere length, even if the regulators are essential genes and a method of regulating telomere length with a PARP inhibitor. VALUE PROPOSITION The researchers developed an in vivo telomere elongation assay...

Published: 9/11/2025 | Inventor(s): Stella Lee, Carol Greider

Keywords(s): Assay, Clinical Diagnostics, Discovery/Research Tools, In Vitro Diagnostics, In Vitro Research Tool

Category(s): Technology Classifications > Research Tools, Technology Classifications > Research Tools > Assays