Search Results - charles+lowenstein

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P-selectin inhibitor, compositions thereof and methods of use thereof

Unmet NeedCOVID-19 is characterized by vascular inflammation and thrombosis, including elevations in P-selectin, a mediator of inflammation released by endothelial cells. Patients with serious infection are more likely to have COVID-19 associated coagulopathy than patients with mild infection, and those who die from COVID-19 are more likely to have...

Published: 3/14/2025 | Inventor(s): Charles Lowenstein

Keywords(s):

Category(s): Clinical and Disease Specializations > Infectious Diseases > Covid-19, Technology Classifications > Therapeutic Modalities, Clinical and Disease Specializations > Inflammation

Inhibitors of N-ethylmaleimide Sensitive Factor

C04180: Inhibitors of N-ethylmaleimide Sensitive Factor Value Proposition: This invention is a novel treatment for thrombotic disorders, such as myocardial infarction, stroke, deep venous thrombosis, pulmonary embolus, hemolytic uremic syndrome, thrombotic thrombocytopenic purpura, sepsis, and microangiopathic hemolytic anemia. This invention may...

Published: 3/13/2025 | Inventor(s): Craig Morrell, Kenji Matsushita, Charles Lowenstein

Keywords(s): Biologics, Cardiovascular Diseases, Disease Indication, Peptide, Therapeutic Matter, Therapeutic Substance, Therapeutics

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Cardiovascular, Technology Classifications > Therapeutic Modalities > Biologics, Technology Classifications > Therapeutic Modalities > Peptides, Technology Classifications > Therapeutic Modalities