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Antisense oligonucleotide therapy and biomarker assay for C9ORF72 hexanucleotide expansion disorders
Therapy to Treat and Assay to Monitor Neurodegenerative Disease JHU REF: [C12195]Invention novelty: This technology is the use of antisense oligonucleotides (ASO) as a therapeutic for specific neurodegenerative diseases. The technology could also be used in development of a biomarker assay to monitor the efficacy of the ASO therapy. Value Proposition: Current...
Published: 3/13/2025
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Inventor(s):
Christopher Donnelly
,
C. Bennett
,
Susan Freier
,
Rita Sattler
,
Jeffrey Rothstein
Keywords(s):
Amyotrophic Lateral Sclerosis
,
Assay
,
Biologics
,
Clinical Diagnostics
,
CNS and Neurological Disorders
,
Dementia
,
Disease Indication
,
In Vitro Diagnostics
,
Neurodegeneration
,
Nucleic Acid
,
Therapeutic Matter
,
Therapeutic Substance
,
Therapeutics
Category(s):
Clinical and Disease Specializations
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Technology Classifications > Therapeutic Modalities > Biologics
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Technology Classifications > Therapeutic Modalities > Gene Therapies
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Technology Classifications > Diagnostics > In Vitro Diagnostics
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Technology Classifications > Research Tools > Assays
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Technology Classifications > Diagnostics
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Clinical and Disease Specializations > Neurology
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Technology Classifications > Research Tools
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Technology Classifications > Therapeutic Modalities
,
Clinical and Disease Specializations > Neurology > Amyotrophic Lateral Sclerosis
,
Clinical and Disease Specializations > Neurology > Dementia
,
Clinical and Disease Specializations > Neurology > Neurodegeneration
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