Search Results - clinical+and+disease+specializations+%3e+gastroenterology+%3e+irritable+bowel+disease

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Gas6-functionalized extracellular vesicles for treatment of inflammatory conditions

Value Proposition· Superior Anti-Inflammatory Potency: This membrane-associated GAS6 demonstrates over 10-fold higher anti-inflammatory activity compared to equivalent amounts of soluble recombinant GAS6 proteins. · Dual Mechanism of Action: Inhibits pro-inflammatory cytokine production and concurrently stimulates anti-inflammatory responses,...

Published: 1/22/2026 | Inventor(s): Kenneth Witwer, Matias Ostrowski, Martina Fabiano, Alan Adamczyk

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Treatment of Irritable Bowel Syndrome with Molybdenum

Unmet NeedIrritable Bowel Syndrome is a chronic and incurable gastrointestinal disorder that affects 3-20% of Americans depending on certain sociocultural and comorbid factors. A poorly understood condition, current treatments consist of antispasmodics, antidiarrheals, and dietary restrictions. Unable to alleviate all its symptoms, researchers are in...

Published: 1/22/2026 | Inventor(s): Pankaj Pasricha, Lian Sheng Liu, Qian Li, Alfred Spormann

Keywords(s): Disease Indication, Gastrointestinal Disorders, Inflammatory Bowel Disease (IBD), Small Molecules, Therapeutic Matter, Therapeutic Substance, Therapeutics

Category(s): Technology Classifications > Therapeutic Modalities > Small Molecules, Clinical and Disease Specializations > Gastroenterology > Irritable Bowel Disease

Method of Treatment of Irritable Bowel Syndrome (KSL-W)

Value Proposition:· A synthetic antimicrobial peptide (AMP) that may be a potent therapeutic for irritable bowel syndrome (IBS) pain.· This AMP limits the growth of harmful bacteria, while not interfering with beneficial ones.· This AMP can be delivered directly to the colon, bypassing any degradation by the upper gastrointestinal...

Published: 1/22/2026 | Inventor(s): Pankaj Pasricha, Qian Li, Lian Sheng Liu, Phillip Phan

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Category(s): Technology Classifications > Therapeutic Modalities > Peptides, Clinical and Disease Specializations > Gastroenterology > Irritable Bowel Disease, Clinical and Disease Specializations > Gastroenterology