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Non-invasive Serological Assay to predict Toxoplasma-associated disease in at-risk populations

Unmet Need: Toxoplasmic Encephalitis (TE) is a life-threatening central nervous system (CNS) disorder that results from the reactivation of a chronic brain infection with Toxoplasma gondii. Chronic T. gondii infection poses a constant and severe danger in situations of immunodeficiency as can occur in HIV infection, organ transplantation, or cancer...

Published: 3/14/2025 | Inventor(s): Jianchun Xiao, Raphael Viscidi, Robert Yolken

Keywords(s):

Category(s): Clinical and Disease Specializations > Infectious Diseases > Toxoplasmosis, Technology Classifications > Diagnostics > In Vitro Diagnostics, Technology Classifications > Research Tools > Assays

Use of Novel Derivatives of Artemisinin To Inhibit Toxoplasma Gondii

C05086: Use of Novel Derivatives of Artemisinin To Inhibit Toxoplasma Gondii Technical Details: Toxoplasmosis, caused by the protozoan Toxoplasma gondii, is a medically important infection that is distributed worldwide. Current treatments for the prevention and treatment of toxoplasmosis are of limited efficacy and have undesirable side-effects. According...

Published: 3/13/2025 | Inventor(s): John D'angelo, Gary Posner, Robert Yolken, Lorraine Brando

Keywords(s): Antagonists/Inhibitors, Disease Indication, Infectious Diseases, Novel, Parasitic Infections, Predicted Novelty, Small Molecules, Therapeutic Matter, Therapeutic Substance, Therapeutics, Toxoplasmosis

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Infectious Diseases > Parasitic Infections, Clinical and Disease Specializations > Infectious Diseases > Toxoplasmosis, Technology Classifications > Therapeutic Modalities > Small Molecules, Clinical and Disease Specializations > Infectious Diseases, Technology Classifications > Therapeutic Modalities