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Orally Administered Metformin to Treat Hair Loss in Central Centrifugal Cicatricial Alopecia

Value Proposition:Potential first-in-class treatment for CCCA, a condition impacting a substantial proportion of Black women. Repurposes metformin, a well-studied and naturally available compound with an established safety profile and a low cost of manufacturing.Oral administration as a simple, self-managed treatment. Unmet Need:Central centrifugal...

Published: 3/14/2025 | Inventor(s): Crystal Aguh

Keywords(s):

Category(s): Clinical and Disease Specializations > Dermatology > Alopecia, Clinical and Disease Specializations > Dermatology, Technology Classifications > Therapeutic Modalities > Repurposed Drugs

Oil based formulation to treat hair loss.

Value Proposition· Non-irritating formulation of minoxidil to treat hair loss· Increased efficacy and tolerance of minoxidil· Suitable for individuals with curly hair· Ointment or oil-based formulation eliminates the need to dissolve minoxidil in irritating vehicleUnmet NeedMinoxidil, which is the only approved medication...

Published: 3/14/2025 | Inventor(s): Crystal Aguh

Keywords(s):

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Dermatology