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Irreversible Inhibitors of DNA Polymerase (Beta)

Unmet Need: Targeted cancer therapies against DNA repair enzymes have successfully been implemented in cancer treatments but now suffer from the development of drug resistance. There is a need for additional DNA repair enzyme targets to overcome current resistance issues. Technical Details: Johns Hopkins researchers have identified an inhibitor of DNA...

Published: 3/13/2025 | Inventor(s): Mohammad Hedayati, Dumitru Arian, Theodore DeWeese, Marc Greenberg

Keywords(s): Antagonists/Inhibitors, Cancers, Disease Indication, Novel, Predicted Novelty, Prostate Cancer, Small Molecules, Therapeutic Matter, Therapeutic Substance, Therapeutics

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Men's Health, Clinical and Disease Specializations > Oncology > Prostate Cancer, Technology Classifications > Therapeutic Modalities > Small Molecules, Clinical and Disease Specializations > Oncology, Technology Classifications > Therapeutic Modalities