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Cell-Permeable Protein Therapeutic for Pain and Itch
Novelty:Identification of a mutant peptide with strong inhibitory effect on nociceptor TRPA1, useful for the prevention and treatment of chronic and acute pain and itch.Value Proposition:Dysregulation of ion channels is associated with various debilitating conditions, including chronic pain and itch. Transient receptor potential ankyrin 1 (TRPA1), an...
Published: 3/13/2025
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Inventor(s):
Hao-Jui Weng
,
Xinzhong Dong
Keywords(s):
Biologics
,
Biomarker
,
Chronic Pain
,
CNS and Neurological Disorders
,
Disease Indication
,
Mechanism of Action Biomarker
,
Peptide
,
Therapeutic Matter
,
Therapeutic Substance
,
Therapeutics
Category(s):
Clinical and Disease Specializations
,
Clinical and Disease Specializations > Neurology
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Technology Classifications > Therapeutic Modalities > Biologics
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Technology Classifications > Therapeutic Modalities > Peptides
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Technology Classifications > Diagnostics > Biomarkers
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Technology Classifications > Therapeutic Modalities > Targets
,
Technology Classifications > Diagnostics
,
Clinical and Disease Specializations > Pain
,
Technology Classifications > Therapeutic Modalities
,
Clinical and Disease Specializations > Pain > Chronic Pain
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